The brain
uses more energy than any other organ in the human body and glucose is its
source of fuel. But what happens when the brain is exposed to the excessive
amount of sugars in the standard American diet? In this case, more is
definitely not better.
In the
brain excess sugar impairs both our cognitive skills and our self-control
(having a little sugar stimulates a craving for more). Sugar has drug-like
effects in the reward center of the brain.
Scientists
have proposed that sweet foods—along with salty and fatty foods—can produce
addiction-like effects in the human brain, driving loss of self-control,
overeating and subsequent weight gain.
In early
humans, this stimulus helped lead them to calorie-rich foods, which aided
survival when food was scare. But now this primitive drive contributes to our
epidemics of obesity and diabetes. The behavioral and neurobiochemical
characteristics of substance abuse and overeating are quite similar, and the
idea of food addiction is gaining ground among scientists.
What Is Reward Response?
In
humans, high-glycemic foods have been found to activate regions of the brain
associated with the reward response and provoke more intense feelings of hunger
compared to low-glycemic foods. Foods that cause a higher elevation in blood
glucose produce a greater addictive drive in the brain.
Studies
on brain activity have provided evidence supporting the idea that overeating
alters our brain’s reward system, which then further drives overeating.
This same
process is thought to underlie the tolerance associated with addiction. Over
time, greater amounts of the substance are required to reach the same level of
reward. Studies imply that overeating results in a diminished reward response
and a progressively worsening addiction to low-nutrient foods rich in sugar,
salt and fat.
What Is the Affect of Excess Sugar on the Body?
Throughout
the body, excess sugar is harmful. Even a single instance of elevated glucose
in the bloodstream can be harmful to the brain, resulting in slowed cognitive
function and deficits in memory and attention.
Sugar
also affects mood. In healthy young people, the ability to process emotion is
compromised with elevated blood glucose, according to a recent brain imaging
study. Another study found that type 2 diabetics increased feelings of sadness
and anxiety during acute hyperglycemia (elevated blood sugar).
What Is the Impact of Elevated Glucose?
Elevated
blood glucose harms blood vessels. Blood vessel damage is the major cause of
the vascular complications of
diabetes, leading
to other problems, such as damage to blood vessels in the brain and eyes
causing retinopathy. Studies of long-term diabetics show progressive brain
damage leading to deficits in learning, memory, motor speed, and other
cognitive functions.
Frequent
exposure to high glucose levels diminishes mental capacity, as higher HbA1c
levels have been associated with a greater degree of brain shrinkage.
Even in
those without diabetes, higher sugar consumption is associated with lower
scores on tests of cognitive function. These effects are thought to be due to a
combination of hyperglycemia, hypertension, insulin resistance, and elevated
cholesterol.
Any sugar
added in our food is dangerous. We can avoid these dangers by satisfying our
sweet tooth with fresh fruit in place of refined sugars. Other
concentrated sweeteners, such as agave, honey, and maple syrup are equally
dangerous. By eating fresh fruit we get the satisfying sweetness
and the added bonus of the fruit’s fiber, antioxidants and phytochemicals that
curtail the surge of sugar in the bloodstream and block its negative effects.
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